Electrostatic charge on a plastic spacer device influences the delivery of salbutamol
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چکیده
منابع مشابه
Electrostatic charge on a plastic spacer device influences the delivery of salbutamol.
The aim of this study was to determine whether electrostatic charge on a plastic spacer decreases the delivery of salbutamol from a pressurized metered-dose inhaler (pMDI) and, if so, to find an optimal and practical treatment to remove the charge. Ten single actuations from a salbutamol pMDI were drawn through different Volumatic spacers at a constant flow of 60 L.min-1. The efficacies of diff...
متن کاملA non-electrostatic spacer for aerosol delivery.
A pear shaped non-electrostatic spacer, composed of steel with a volume of 250 ml and equipped with a facemask containing integrated inlet and outlet valves for inspiration and expiration, was compared with three plastic spacers. The plastic spacers were primed with repeated puffs from a budesonide pressurised metered dose inhaler (p-MDI) to minimise the electrostatic charge on the plastic. The...
متن کاملEffect of electrostatic charge, flow, delay and multiple actuations on the in vitro delivery of salbutamol from different small volume spacers for infants.
BACKGROUND A study was undertaken to determine the influences of electrostatic charge, flow, delay, and multiple actuations on the in vitro delivery of salbutamol generated by a pressurised metered dose inhaler (pMDI) from small volume spacers used in infants. METHODS Ten actuations from a salbutamol pMDI were drawn at different flow rates after either single or multiple actuations, with or w...
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Ionic detergents reduce electrostatic charge on plastic spacers, thereby improving in vitro drug delivery. The aim of this study was to gain practical information on the use of detergents and to evaluate the relevance of this information on in vivo drug deposition. Measurement of electrostatic charge and salbutamol particle size distribution was carried out on detergent-coated and noncoated pla...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 1996
ISSN: 0000-0000,0903-1936
DOI: 10.1183/09031936.96.09091943